​Why Orbone?

The Orbone® Cell and Tissue Bank is a class B GMP licensed facility that processes a wide range of human-derived tissues with a focus on collecting, storing, and processing bone, soft tissues and tissue components. Using licensed and proprietary eCOO® supercritical carbon dioxide technology, it provides superior quality, safe, clean, and innovative products to the Allograft industry.

Traditional cleaning and sterilization methods are generally used in hard bone treatments that affect the mechanical or structural properties of tissue grafts. Several studies show that these methods have detrimental effects on protein structure, adsorption rate, cell adhesion and tensile strength. These procedures also demand meticulous rinsing procedures and very time-consuming procedures.
Conversely, cleaning of tissues with the Orbone® Cell and Tissue Bank’s eCOO® Clean Technology and subsequent eCOO® Ster sterilization minimally affects the structural integrity of the tissue. So far, the sterile level and virus inactivation have reached SAL6. Biomolecular properties (e.g., protein degradation and cell attachment) and mechanical properties (i.e., tensile strength and extreme torque) are retained to support the weight-bearing and/or sensitive application stress of tissue grafts required for tissue-related processing/sterilization using eCOO® scCO2 Technology. 

Why Orbone Tissue Bank

We support the following opportunities in delivering them to you:

  • B2B model for R&D and production
  • Allograft information support programs for our physicians
  • End-to-end service solutions
  • Custom production and scaling options
  • International distribution and sales opportunities

In addition, the system has been adapted to meet the specific requirements of the tissue and to leave a minimal carbon footprint. The technology has also been modified to minimize its carbon impact and to satisfy the unique needs of the tissue.
Experience with decellularization processes, virus inactivation techniques employing eCOO® technology, and an extra USP add to the product in the case of product development.

The Orbone® Cell and Tissue Bank is a GMP licensed facility that processes a wide range of human-derived tissues with a focus on collecting, storing, and processing bone, soft tissues and tissue components. Using licensed and proprietary eCOO® scCO2 technology, it provides superior quality, safe, clean and innovative products to the Allograft industry.

We are different, Orbone® produces tissue and bone grafts in all its varieties, mainly in class A, for orthopedics and traumatology, neurosurgery, maxillofacial and dental surgery, in cGMP and ISO certified, class B production laboratories. With our skilled workers in the fields of Bioengineering and Molecular and Genetics, who appeals to the fields of Orthopedics and Dental Tissue Engineering, we work on cleaning, sterilizing, and grafting tissues using the superior production quality and special qualities of eCOO® scCO2 technology, we provide many different surgical Allograft alternatives such as conventional bones, soft tissues, and special products for transplantation. Orbone® serves the medical community across the world and is a center of excellence in the development and production of human-derived tissues. eCOO® scCO2 technology is a proprietary tissue production platform patented by the Netherlands Tissue Bank EMCM, producing high quality human-sourced tissues, and brought to Turkey by the technology transfer of Orbone® Cell and Tissue Bank. Orbone® keeps working to advance its technology and products in an effort to improve the patient’s recuperation. Our tissue bank, which aims to lead and serve the tissue industry scientifically since its establishment, continues its Allograft R&D studies with tissue banks in Europe. Orbone® Cell and Tissue Bank, which accompanies business development platforms with high-quality licensed Tissue Banks in the world, continues to represent and develop Türkiye successfully in this sector.